ISO 10R COP Vial, Sterile, Tray of 140pc

ISO 10R COP (Cyclic Olefin Polymer) vials, 24x45mm, 20mm crimp, sealed plastic tray of 140 pieces.

20mm seals and 20mm stoppers sold separately. Sterilized by e-beam processing. 

Benefits of COP Vials:

·         Enhanced Integrity at Low Temperatures: COP vials maintain container closure integrity (CCI) at ultra-low (cryogenic) temperatures, which is crucial for sensitive biologics and cell therapies. Unlike glass, which can become brittle and lose CCI due to differing thermal expansion rates between glass and rubber stoppers, COP and rubber shrink at comparable rates, preventing gap formation [COP Vials at pda.org].

·         Reduced Breakage Risk: Glass is inherently brittle, and this brittleness increases at low temperatures, making it prone to fracture during handling and shipping. COP vials are fracture-resistant, leading to fewer product losses and enhanced safety [pharmaceuticalonline.com].

·         Minimal Drug Interaction: COP is highly inert, meaning it has a lower propensity to interact with the drug product. Glass, on the other hand, can leach substances or experience delamination (shedding of glass flakes), potentially compromising drug efficacy and safety. The FDA has even issued advisories regarding delamination with glass vials [COP Vials at pda.org].

·         Superior Barrier Properties: COP vials offer good resistance to oxygen and water, which helps protect oxygen-sensitive and moisture-sensitive medications [pharmaceuticalonline.com, industryintel.com].

·         Clarity and Transparency: Despite being a polymer, COP maintains excellent clarity, similar to glass, allowing for easy visual inspection of the contents [industryintel.com].

STERILIZED BY E-BEAM PROCESSING: E-beam sterilization of Cyclic Olefin Polymer (COP) vials offers a fast, precise, and highly efficient terminal sterilization method, especially for sensitive pharmaceutical and biological products. The high-energy, short-duration electron beam provides superior material compatibility with low degradation compared to gamma or ETO, ensuring, for example, that COP vials maintain their high transparency.